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Next, we compared cell responses to TNC with that to TGF-β and, found that similar to TNC, TGF-β induces an EMT in NT193 cells as evidenced by loss of E-cadherin and gain of vimentin expression (Fig. 6A-C, Fig. S6A, B). Notably, the TGF-β signaling inhibitor GW788388 (GW)...
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we observed additive effects of XDH inhibition and TGFβ1 in HepG2 cells, which supports the increased response to TGFβ1 treatment in Oncogenesis (2017), 1 – 10 XDH loss promotes HCC metastasis through TGFβ signaling G-L Chen et al 6 DMSO GW788388 Pirfenidone 20 * * 15 ns 10 ns...
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